Article
Molecular and genetic characterization of a radiation-induced structural rearrangement in mouse chromosome 2 causing mutations at the limb deformity and agouti loci.
Proceedings of the National Academy of Sciences of the United States of America - 1 Apr 1990
Woychik R P, Generoso W M, Russell L B, Cain K T, Cacheiro N L, Bultman S J, Selby P B, Dickinson M E, Hogan B L, Rutledge J C
Abstract excerpt
Molecular characterization of mutations in the mouse, particularly those involving agent-induced major structural alterations, is proving to be useful for correlating the structure and expression of individual genes with their function in the whole organism. Here we present the characterization o...
Topics
- Abnormalities, Radiation-Induced
- Animals
- Chromosome Aberrations
- Chromosome Banding
- Chromosome Disorders
- Chromosomes
- Cloning, Molecular
- Crosses, Genetic
- Female
- Gamma Rays
- Homozygote
- Karyotyping
- Male