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Article

CUX1 transcription factor is a downstream effector of the proteinase-activated receptor 2 (PAR2).

The Journal of biological chemistry - 2 Jan 2009

Wilson Brian J, Harada Ryoko, LeDuy Lam, Hollenberg Morley D, Nepveu Alain

Abstract excerpt

Proteinase-activated receptors (PARs) are G-protein-coupled receptors that have been linked to an array of cellular processes, including inflammation, migration, and proliferation. Although signal transduction downstream of PARs has been actively investigated, little is known about the mechanisms that lead to changes in transcriptional programs. Here we show that the CUX1 homeodomain protein is a downstream...

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Source

Identifiers

PMID: 18952606
DOI: 10.1074/jbc.M803808200

Genes

CUX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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