Article
Cloning and characterization of human protease-activated receptor 4.
Proceedings of the National Academy of Sciences of the United States of America - 9 Jun 1998
Xu W F, Andersen H, Whitmore T E, Presnell S R, Yee D P, Ching A, Gilbert T, Davie E W, Foster D C
Abstract excerpt
Protease-activated receptors 1-3 (PAR1, PAR2, and PAR3) are members of a unique G protein-coupled receptor family. They are characterized by a tethered peptide ligand at the extracellular amino terminus that is generated by minor proteolysis. A partial cDNA sequence of a fourth member of this fam...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Humans
- Inositol 1,4,5-Trisphosphate
- Molecular Sequence Data
- Mutation
- Receptors, Cell Surface
- Receptors, Thrombin
- Sequence Analysis
- Transfection