Article
The multiple roles of CUX1: insights from mouse models and cell-based assays.
Gene - 15 Apr 2008
Sansregret Laurent, Nepveu Alain
Abstract excerpt
Cux (Cut homeobox) genes are present in all metazoans. Early reports described many phenotypes caused by cut mutations in Drosophila melanogaster. In vertebrates, CUX1 was originally characterized as the CCAAT-displacement protein (CDP). Another line of investigation revealed the presence of CUX1 within a multi-protein complex called the histone nuclear factor D (HiNF-D). Recent studies led to the identification...
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