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The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1

1 Jan 1994

Abstract excerpt

POU5F1, which encodes a transcriptional factor, has two alternatively spliced transcripts, 1 and 2, as well as six pseudogenes. Transcript 1 is considered to be a key regulator of cellular pluripotency and self-renewal. The POU5F1 pseudogene, POU5F1P1 on 8q24, encodes a protein with 95% homology with the isoform 1 of POU5F1. It is located 15 kbp downstream of the SNP rs6983267, which is strongly associated with...

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PMID: 18949397
DOI: 10.3892/or_00000105

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