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Article

<i>EWSR1</i> is fused to <i>POU5F1</i> in a bone tumor with translocation t(6;22)(p21;q12)

23 Feb 2005

Abstract excerpt

POU5F1(OCT3/4) is a sequence-specific transcription factor that is essential for keeping germ cells and embryonic stem cells in an immature and pluripotent status. In this article, we report that POU5F1 was fused to EWSR1 in a case of undifferentiated sarcoma derived from pelvic bone with chromosomal translocation t(6;22)(p21;q12). The EWSR1-POU5F1 chimera consists of exons 1-6 of EWSR1 and exons 2-5 and a part...

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Identifiers

PMID: 15729702
DOI: 10.1002/gcc.20171

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