Article
POU5F1P1, a putative cancer susceptibility gene, is overexpressed in prostatic carcinoma.
The Prostate - 1 May 2010
Kastler Silvia, Honold Lisa, Luedeke Manuel, Kuefer Rainer, Möller Peter, Hoegel Josef, Vogel Walther, Maier Christiane, Assum Guenter
Abstract excerpt
BACKGROUND: Association between genetic variants located on human chromosome 8q24.21 with an increased risk for prostatic carcinoma has been well established. POU5F1P1, a processed pseudogene homologous to the pluripotency factor OCT4, is the only sequence with coding capacity in this region. The objective of this study was to investigate the POU5F1P1 expression in prostatic carcinoma and carcinoma surrounding...
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