Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequence variation in the human transcription factor gene POU5F1.

BMC genetics - 6 Feb 2008

Hussain Shehnaz K, Sequerra Reynaldo, Bertucci Caterina, Hastings Noel C, Rieder Mark, Schwartz Stephen M

Abstract excerpt

BACKGROUND: POU5F1 expression is required to maintain stem cell pluripotency and for primordial germ cells to retain proliferative capability in embryonic development. Recent evidence suggests that POU5F1 may also be a testicular germ cell carcinoma (TGCC) oncogene, and POU5F1 variation may influence TGCC risk. As an important first step to a genetic association study, we sought to identify all common sequence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Linkage
Share to Genetic Variation
Share to Genomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Octamer Transcription Factor-3

Share to Phylogeny

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 18254969
DOI: 10.1186/1471-2156-9-15
PMCID: PMC2275747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence variation in the human transcription factor gene POU5F1.PMID 18254969Read ↗

Potentially Functional Polymorphisms in POU5F1 Gene Are Associated with the Risk of Lung Cancer in Han Chinese.Semantic proximity Read ↗

The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1Semantic proximity Read ↗

An expressed retrogene of the master embryonic stem cell gene POU5F1 is associated with prostate cancer susceptibility.Semantic proximity Read ↗

Evaluation of regulatory genetic variants in POU5F1 and risk of congenital heart disease in Han Chinese.Semantic proximity Read ↗

Germline variation in the 3'-untranslated region of the POU2AF1 gene is associated with susceptibility to lymphoma.Semantic proximity Read ↗

POU5F1P1, a putative cancer susceptibility gene, is overexpressed in prostatic carcinoma.Semantic proximity Read ↗

Polymorphisms in intron 1 of the porcine POU1F1 gene.Semantic proximity Read ↗

High-throughput splicing assays identify missense and silent splice-disruptive<i>POU1F1</i>variants underlying pituitary hormone deficiencySemantic proximity Read ↗

A novel mutation in POFUT1 gene associated with Dowling-Degos disease and hidradenitis suppurativa.Semantic proximity Read ↗

Functional characterization of single-nucleotide polymorphisms in the human undifferentiated embryonic-cell transcription factor 1 gene.Semantic proximity Read ↗

Association of the POU class 2 homeobox 1 gene (POU2F1) with susceptibility to Type 2 diabetes in Chinese populations.Semantic proximity Read ↗

New candidate gene POU5F1 associated with premature ovarian failure in Chinese patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.