Article
A functional haplotype in the 3'untranslated region of TNFRSF1B is associated with tuberculosis in two African populations.
American journal of respiratory and critical care medicine - 15 Feb 2010
Möller Marlo, Flachsbart Friederike, Till Andreas, Thye Thorsten, Horstmann Rolf D, Meyer Christian G, Osei Ivy, van Helden Paul D, Hoal Eileen G, Schreiber Stefan, Nebel Almut, Franke Andre
Abstract excerpt
RATIONALE: Susceptibility to tuberculosis is not only determined by Mycobacterium tuberculosis infection, but also by the genetic component of the host. The pleiotropic cytokine tumor necrosis factor-alpha is essential to control tuberculosis infection, and various tumor necrosis factor family me...
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