Article
The MCP-1 (CCL2) -2518 GG genotype is associated with protection against pulmonary tuberculosis in Moroccan patients.
Journal of infection in developing countries - 12 Jan 2012
Arji Naima, Busson Marc, Iraqi Ghali, Bourkadi Jamal Eddine, Benjouad Abdelaziz, Boukouaci Wahid, Lahlou Ouafae, Ben Amor Jouda, Krishnamoorthy Rajagopal, Charron Dominique, El Aouad Rajae, Tamouza Ryad
Abstract excerpt
INTRODUCTION: Both monocyte chemoattractant protein-1 (MCP-1), also designated officially as chemokine (C-C motif) ligand 2 (CCL2), and interleukin-12 p40 (IL-12 p40) molecules, encoded by polymorphic genes, are central components of the immune response to infection by Mycobacterium tuberculosis (Mtb). Their genetic diversity has previously been associated with the outcome of tuberculosis (TB) infection. We...
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