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Dynamic Changes in Lymphocyte Populations Establish Zebrafish as a Thymic Involution Model

2023-07-27

Abstract excerpt

The thymus is the site of T lymphocyte development and T cell education to recognize foreign, but not self, antigens. B cells also reside and develop in the thymus, although their functions are less clear. During ‘thymic involution,’ a process of lymphoid atrophy and adipose replacement linked to sexual maturation, thymocytes decline. However, thymic B cells decrease far less than T cells, such that B cells compri...

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Literature Corpus work
6f4ab727-9a42-50f8-9d6a-5a22720940e7
DOI
10.1101/2023.07.25.550519
Open publication

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Dynamic Changes in Lymphocyte Populations Establish Zebrafish as a Thymic Involution ModelDOI 10.1101/2023.07.25.550519
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