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Article

Sex hormones have pervasive effects on thymic epithelial cells

7 Aug 2015

Abstract excerpt

The goal of our study was to evaluate at the systems-level, the effect of sex hormones on thymic epithelial cells (TECs). To this end, we sequenced the transcriptome of cortical and medullary TECs (cTECs and mTECs) from three groups of 6 month-old mice: males, females and males castrated at four weeks of age. In parallel, we analyzed variations in the size of TEC subsets in those three groups between 1 and 12...

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PMID: 26250469
DOI: 10.1038/srep12895

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