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Article

Colorimetric detection of single nucleotide polymorphisms in the presence of 10³-fold excess of a wild-type gene.

Biosensors & bioelectronics - 15 Jun 2015

Deng Huimin, Shen Wei, Gao Zhiqiang

Abstract excerpt

Herein, we proposed a simple colorimetric assay for highly sensitive and specific detection of single nucleotide polymorphisms (SNPs). Briefly, SNP specific capture probes (CPs) were immobilized onto magnetic beads. The hybridization of a target SNP with the CPs and detection probes containing multiple DNAzyme sequences (DNAzyme-DPs) brought the target SNP and the DNAzyme-DPs onto the magnetic beads. Meanwhile, a...

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PMID: 25596559
DOI: 10.1016/j.bios.2015.01.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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