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Article

Detection of single nucleotide polymorphisms by the combination of nuclease S1 and PNA.

Nucleic acids research. Supplement (2001) - 1 Jan 2002

Ye Sheng, Liang Xingguo, Yamamoto Yoji, Komiyama Makoto

Abstract excerpt

A very simple and practical genotyping method has been developed by combining peptide nucleic acid (PNA) and nuclease S1. The portion in the sample DNA, which is complementary with PNA (either completely or partially), is protected from the enzymatic digestion, providing the DNA fragments of pred...

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Identifiers

PMID: 12903192
DOI: 10.1093/nass/2.1.235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12903192-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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