Article
Autophagy genes function in apoptotic cell corpse clearance during C. elegans embryonic development.
Autophagy - 1 Feb 2013
Huang Shuyi, Jia Kailiang, Wang Ying, Zhou Zheng, Levine Beth
Abstract excerpt
Efficient apoptotic corpse clearance is essential for metazoan development and adult tissue homeostasis. Several autophagy proteins have been previously shown to function in apoptotic cell clearance; however, it remains unknown whether autophagy genes are essential for efficient apoptotic corpse clearance in the developing embryo. Here we show that, in Caenorhabditis elegans embryos, loss-of-function mutations in...
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