Article
Phenotypic modulation in lipocytes in experimental liver fibrosis.
The Journal of pathology - 1 Jul 1991
Tanaka Y, Nouchi T, Yamane M, Irie T, Miyakawa H, Sato C, Marumo F
Abstract excerpt
The presence of a-smooth muscle actin (smA)-positive cells has recently been reported in the fibrotic liver. Lipocytes have been considered to play important roles in hepatic fibrosis. However, the relation of the a-smA-positive cells and lipocytes has not been determined. The biological implication of a-smA expression remains unknown. To study these questions, we carried out double immunofluorescent staining of...
Topics
- Actins
- Animals
- Bromodeoxyuridine
- Collagen
- Desmin
- Fluorescent Antibody Technique
- Immunohistochemistry
- Liver
- Liver Cirrhosis, Experimental
- Male
- Phenotype
- Rats