Article
Phenotypic Changes in Macrophage Activation in a Model of Nonalcoholic Fatty Liver Disease using Microminipigs.
Journal of atherosclerosis and thrombosis - 1 Aug 2021
Yoshii Daiki, Nakagawa Takenobu, Komohara Yoshihiro, Kawaguchi Hiroaki, Yamada Sohsuke, Tanimoto Akihide
Abstract excerpt
AIM: Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disorders associated with metabolic syndrome, and its prevalence has been on the rise. The pathogenesis of NAFLD has not yet been sufficiently elucidated due to the multifactorial nature of the disease, although the activation of macrophages/Kupffer cells is considered to be involved. We previously reported an animal model of...
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