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Article

Regulation of the mesangial cell myofibroblast phenotype by actin polymerization.

Journal of cellular physiology - 1 Jun 2003

Patel Keyur, Harding Pamela, Haney Lisa B, Glass William F

Abstract excerpt

Mesangial cells in diverse glomerular diseases become myofibroblast-like, characterized by activation of smooth muscle alpha-actin (alpha-SMA) expression. In cultured mesangial cells, serum-deprivation markedly increases alpha-SMA expression, cell size, and stress fiber formation. Since stress fibers are assembled from actin monomers, we investigated the hypothesis that alterations in stress fiber formation...

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Identifiers

PMID: 12704653
DOI: 10.1002/jcp.10267

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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