Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.

doi:10.1016/j.biopsych.2009.08.030

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Article

Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.

Biological psychiatry - 1 Feb 2010

Ikeda Masashi, Tomita Yasuyuki, Mouri Akihiro, Koga Minori, Okochi Tomo, Yoshimura Reiji, Yamanouchi Yoshio, Kinoshita Yoko, Hashimoto Ryota, Williams Hywel J, Takeda Masatoshi, Nakamura Jun, Nabeshima Toshitaka, Owen Michael J, O'Donovan Michael C, Honda Hiroyuki, Arinami Tadao, Ozaki Norio, Iwata Nakao

Abstract excerpt

BACKGROUND: Pharmacogenomic approaches based on genomewide sets of single nucleotide polymorphisms (SNPs) are now feasible and offer the potential to uncover variants that influence drug response. METHODS: To detect potential predictor gene variants for risperidone response in schizophrenic subjects, we performed a convergent analysis based on 1) a genomewide (100K SNP) SNP pharmacogenetic study of risperidone...

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Identifiers

PMID: 19850283
DOI: 10.1016/j.biopsych.2009.08.030

Genes

AJAP1
BAG3
EPHA6
KCNH5
PAICS
PTGFRN
ZBTB20

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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