Article
Characterization of survival and phenotype throughout the life span in UCP2/UCP3 genetically altered mice.
Experimental gerontology - 1 Dec 2008
McDonald Roger B, Walker Keya M, Warman David B, Griffey Stephen M, Warden Craig H, Ramsey Jon J, Horwitz Barbara A
Abstract excerpt
In the present investigation we describe the life span characteristics and phenotypic traits of ad libitum-fed mice that overexpress UCP2/3 (Positive-TG), their non-overexpressing littermates (Negative-TG), mice that do not expression UCP2 (UCP2KO) or UCP3 (UCP3KO), and wild-type C57BL/6J mice (WT-Control). We also included a group of C57BL/6J mice calorie-restricted to 70% of ad libitum-fed mice in order to test...
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