Article
Body weight is not always a good predictor of longevity in mice.
Experimental gerontology - 1 Mar 2004
Anisimov Vladimir N, Arbeev Konstantin G, Popovich Irina G, Zabezhinksi Mark A, Rosenfeld Svetlana V, Piskunova Tatiana S, Arbeeva Lyubov S, Semenchenko Anna V, Yashin Anatoli I
Abstract excerpt
There have been some observations that low body weight and a low level of some hormones (e.g. IGF-1) during the first half of life are predictors of longer life in mice. However, contradictions in the available data on the biomarkers of aging and predictors of longevity have shown that the research in these fields has become a controversial pursuit. In our study we addressed the following questions: (i) Can...
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