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Article

The Influence of Shc Proteins on Life Span in Mice

14 Dec 2013

Abstract excerpt

The signaling molecule p66Shc is often described as a longevity protein. This conclusion is based on a single life span study that used a small number of mice. The purpose of the present studies was to measure life span in a sufficient number of mice to determine if longevity is altered in mice with decreased Shc levels (ShcKO). Studies were completed at UC Davis and the European Institute of Oncology (EIO). At...

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Identifiers

PMID: 24336818
DOI: 10.1093/gerona/glt198

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