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Article

WNT signaling promotes Nkx2.5 expression and early cardiomyogenesis via downregulation of Hdac1.

Biochimica et biophysica acta - 1 Feb 2009

Liu Zhiqiang, Li Tao, Liu Yinan, Jia Zhuqing, Li Yanming, Zhang Chenguang, Chen Ping, Ma Kangtao, Affara Nabeel, Zhou Chunyan

Abstract excerpt

The cardiac transcription factor NKX2.5 plays a crucial role in cardiomyogenesis, but its mechanism of regulation is still unclear. Recently, epigenetic regulation has become increasingly recognized as important in differentiation and development. In this study, we used P19CL6 cells to investigat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18851995
DOI: 10.1016/j.bbamcr.2008.08.013

Genes

SFRP2
WNT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18851995-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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