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Article

Early changes in murine epidermal cell phenotype by contact sensitizers.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Mar 1999

Coutant K D, Ulrich P, Thomas H, Cordier A, Brugerolle de Fraissinette A

Abstract excerpt

In order to develop an in vitro predictive assay for the detection of contact sensitizers, we investigated the possible modulation of the expression of cell-surface molecules in the early phases of treatment of murine epidermal cells (EC) with known contact sensitizers. After in vitro treatment of Balb/c EC with the strong contact sensitizer, TNBS, Langerhans cells (LCs) demonstrated a rapid up-regulation of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10330686
DOI: 10.1093/toxsci/48.1.74

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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