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Article

Can the KG1 cell line be used as a model of dendritic cells and discriminate the sensitising potential of chemicals?

Toxicology letters - 19 Nov 2015

Curtis Angela, Morton Jackie, Fraser Susan, Harding Anne-Helen, Prideaux Brendan, Clench Malcom, Warren Nicholas D, Evans Gareth S

Abstract excerpt

The KG1 myeloid leukaemia was used as source of dendritic cells (DC) to discriminate between respiratory and contact sensitising chemicals. A cocktail of cytokines was used to differentiate KG1 to dendritic like cells (termed dKG1) and the effects of nine chemicals (respiratory and contact sensitisers) and an irritant control on surface marker expression, 'antigen presenting' function and cytokine expression...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26260117
DOI: 10.1016/j.toxlet.2015.08.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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