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Article

Haptoglobin genotype is a major determinant of the amount of iron in the human atherosclerotic plaque.

Journal of the American College of Cardiology - 23 Sept 2008

Moreno Pedro R, Purushothaman K Raman, Purushothaman Meera, Muntner Paul, Levy Nina S, Fuster Valentin, Fallon John T, Lento Patrick A, Winterstern Aaron, Levy Andrew P

Abstract excerpt

OBJECTIVES: We sought to test the hypothesis that haptoglobin (Hp) genotype is a determinant of the amount of iron in the atherosclerotic plaque. BACKGROUND: In atherosclerotic lesions, intraplaque hemorrhage releases free hemoglobin (Hb), whose incorporated iron can act as an oxidant and inflamm...

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Identifiers

PMID: 18848136
DOI: 10.1016/j.jacc.2008.06.029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18848136-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Haptoglobin genotype is a major determinant of the amount of iron in the human atherosclerotic plaque.PMID 18848136Read ↗

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