Article
Haptoglobin genotype 2-2 associated with atherosclerosis in patients with ischemic stroke.
Gene - 20 Aug 2020
Merkler A, Sertić J, Bazina Martinović A, Križ T, Miličić I, Šimić M, Caban D, Ljubić H, Markeljević J, Šimičević L, Kaštelan S, Pećin I, Reiner Ž
Abstract excerpt
AIM: Ischemic stroke (IS) is multifactorial disease and therefore different genes and proteins play a role in its development. Haptoglobin (Hp) removes free hemoglobin and protects from iron-induced oxidative damage, inflammatory response, atherosclerosis and cerebrovascular diseases. The aim of this study was to investigate Hp genetic variants in patients with carotid atherosclerotic lesions and IS. MATERIAL AND...
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