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Article

Identification of amino acid residues in PEPHC1 important for binding to the tumor-specific receptor EGFRvIII.

Chemical biology & drug design - 1 Oct 2008

Hansen Charlotte Lund, Hansen Paul Robert, Pedersen Nina, Poulsen Hans Skovgaard, Gillings Nic, Kjaer Andreas

Abstract excerpt

EGFRvIII is a cancer-specific epidermal growth factor tyrosine kinase receptor mutation, expressed in different kinds of cancer, in particular ovarian, glioblastomas, and breast cancer. A peptide, PEPHC1, has previously been shown to bind selectively to EGFRvIII. An alanine scan was performed to...

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PMID: 18844673
DOI: 10.1111/j.1747-0285.2008.00706.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18844673-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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