Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer Targeting Radiopeptidomimetics in Molecular Nuclear Medicine

13 Mar 2025

Abstract excerpt

Peptides are highly receptor-affine molecules exhibiting suitable pharmacokinetics. Additionally, low-cost production, simple protocols allowing easy modifications, and tolerance toward harsh reaction conditions make peptides ideal ligands for preparation of radiopharmaceuticals for cancer detection and treatment. However, natural peptides being substrates for enzymes are susceptible to proteolysis, which limits...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemical Synthesis and Analysis
Share to Peptidase Inhibition and Analysis
Share to Radiopharmaceutical Chemistry and Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40078059
DOI: 10.1021/acs.molpharmaceut.4c01180

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer Targeting Radiopeptidomimetics in Molecular Nuclear MedicinePMID 40078059Read ↗

Molecular imaging probes derived from natural peptidesSemantic proximity Read ↗

Precision medicine by designer interference peptides: applications in oncology and molecular therapeuticsSemantic proximity Read ↗

Anticancer Peptides: Design Principles, Translational Bottlenecks, and Emerging OpportunitiesSemantic proximity Read ↗

Mapping the Modification Landscape of MHC-I Epitopes: A Framework for Immunogenic Peptidomimetic Antigen DesignSemantic proximity Read ↗

Exploring tryptamine conjugates as pronucleotides of phosphate-modified 7-methylguanine nucleotides targeting cap-dependent translation.Semantic proximity Read ↗

γ-Amino Carboxylic Acid Modification Enhances the Efficacy of PNAs Targeting miR-221-3p in A549 CellsSemantic proximity Read ↗

Identification of novel peptide ligands for the cancer-specific receptor mutation EFGRvIII using a mixture-based synthetic combinatorial library.Semantic proximity Read ↗

Molecular avenues in targeted doxorubicin cancer therapySemantic proximity Read ↗

Design and investigation of interactions of novel peptide conjugates of purine and pyrimidine derivatives with EGFR and its mutant T790M/L858R: an in silico and laboratory study.Semantic proximity Read ↗

Computer-aided design of amino acid-based therapeutics: a reviewSemantic proximity Read ↗

Labelled Oligonucleotides as Radiopharmaceuticals: Pitfalls, Problems and PerspectivesSemantic proximity Read ↗

Exploration of Bicyclic Peptide Ligands for Immune-Specific PET Imaging: Targeting Tumor PD-L1 with [18F]AlF-BCY10959Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.