Article

Structural basis for the identification of short novel peptides as potential GLP1R agonists using in silico approaches

2022-06-23

Abstract excerpt

<title>Abstract</title> <p>Glucagon-like peptide-1 receptor (GLP-1R) agonists are effective anti-diabetic drugs that improve energy balance by increasing glucose-dependent insulin production. Currently numerous GLP-1 peptides are marketed and few small molecular agonists are in clinical trial stage. GLP-1 is a 31 amino acid peptide and the marketed peptides are even larger or of similar length residue peptides. T...

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Literature Corpus work: 219f00ba-f488-57db-8d4d-aea29a512823
DOI: 10.21203/rs.3.rs-1721735/v1

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