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Article

Synthesis and physicochemical studies of amyloidogenic hexapeptides derived from human cystatin C.

Journal of peptide science : an official publication of the European Peptide Society - 1 Jun 2018

Iłowska Emilia, Sawicka Justyna, Szymańska Aneta

Abstract excerpt

Human cystatin C (hCC) is a low molecular mass protein that belongs to the cystatin superfamily. It is an inhibitor of extracellular cysteine proteinases, present in all human body fluids. At physiological conditions, hCC is a monomer, but it has a tendency to dimerization. Naturally occurring hCC mutant, with leucine in position 68 substituted by glutamine (L68Q), is directly involved in the formation of amyloid...

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PMID: 29573035
DOI: 10.1002/psc.3073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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