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Article

Association of the apolipoprotein E gene, its promoter polymorphisms and haplotypes with depressive symptoms. The Cardiovascular Risk in Young Finns Study.

Neuropsychobiology - 1 Jan 2008

Elovainio Marko, Puttonen Sampsa, Pulkki-Råback Laura, Kivimaki Mika, Viiri Leena E, Lehtimaki Terho, Karhunen Pekka, Viikari Jorma, Raitakari Olli T, Keltikangas-Jarvinen Liisa

Abstract excerpt

OBJECTIVES: Evidence on apolipoprotein E (APOE) gene as a vulnerability factor for depression is mixed. Polymorphisms of the APOE gene regulatory region may serve as additional explanatory factors, as they help in explaining variation of depressive symptoms within the APOE epsilon2/epsilon3/epsilon4 genotype groups. In this study, the associations of the APOE gene promoter polymorphisms -219G/T and +113G/C and...

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Identifiers

PMID: 18843194
DOI: 10.1159/000162355

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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