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Article

ApoE plasma levels and risk of cardiovascular mortality in old age.

PLoS medicine - 1 Jun 2006

Mooijaart Simon P, Berbée Jimmy F P, van Heemst Diana, Havekes Louis M, de Craen Anton J M, Slagboom P Eline, Rensen Patrick C N, Westendorp Rudi G J

Abstract excerpt

BACKGROUND: The epsilon2, epsilon3, and epsilon4 alleles of the apolipoprotein E gene (APOE) encode three isoforms, apoE2, E3, and E4, respectively. The apoE isoforms circulate in different plasma concentrations, but plasma concentrations of the same isoform also differ between individuals. Whereas the isoforms have been associated with cardiovascular disease, the relation between plasma apoE levels and...

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Source

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Identifiers

PMID: 16671834
DOI: 10.1371/journal.pmed.0030176
PMCID: PMC1457005

Genes

CRP
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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