Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relations of APOE promoter polymorphisms to LDL cholesterol and markers of subclinical atherosclerosis in young adults.

Journal of lipid research - 1 Jun 2006

Viiri Leena E, Raitakari Olli T, Huhtala Heini, Kähönen Mika, Rontu Riikka, Juonala Markus, Hutri-Kähönen Nina, Marniemi Jukka, Viikari Jorma S A, Karhunen Pekka J, Lehtimäki Terho

Abstract excerpt

The common apolipoprotein E (apoE) gene (APOE) epsilon2/epsilon3/epsilon4 polymorphism explains part of serum lipid variation, and polymorphisms in the APOE promoter region have been proposed to participate in the regulation of serum lipid levels within the most common APOE epsilon3/epsilon3 genotype group. We determined APOE -219G/T and +113G/C promoter genotypes and estimated APOE haplotypes in 525 participants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Atherosclerosis

Share to Biomarkers

Share to Cholesterol

Share to Cholesterol, HDL

Share to Cholesterol, LDL

Share to Longitudinal Studies

Source

Identifiers

PMID: 16528057
DOI: 10.1194/jlr.M600033-JLR200

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relations of APOE promoter polymorphisms to LDL cholesterol and markers of subclinical atherosclerosis in young adults.PMID 16528057Read ↗

Association of the apolipoprotein E gene, its promoter polymorphisms and haplotypes with depressive symptoms. The Cardiovascular Risk in Young Finns Study.Semantic proximity Read ↗

Associations of apolipoprotein E gene with ischemic stroke and intracranial atherosclerosis.Semantic proximity Read ↗

Association of APOE epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age.Semantic proximity Read ↗

Interactions of functional apolipoprotein E gene promoter polymorphisms with smoking on aortic atherosclerosis.Semantic proximity Read ↗

Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants.Semantic proximity Read ↗

Variation in 5' promoter region of the APOE gene contributes to predicting ischemic heart disease (IHD) in the population at large: the Copenhagen City Heart Study.Semantic proximity Read ↗

Contributions of 18 additional DNA sequence variations in the gene encoding apolipoprotein E to explaining variation in quantitative measures of lipid metabolism.Semantic proximity Read ↗

Association and linkage disequilibrium analyses of APOE polymorphisms in atherosclerosis.Semantic proximity Read ↗

Apolipoprotein E phenotypes in Finnish youths: a cross-sectional and 6-year follow-up study.Semantic proximity Read ↗

Associations of LPL and APOC3 gene polymorphisms on plasma lipids in a Mediterranean population: interaction with tobacco smoking and the APOE locus.Semantic proximity Read ↗

Influence of apolipoprotein E polymorphism on serum lipid and lipoprotein changes: a 21-year follow-up study from childhood to adulthood. The Cardiovascular Risk in Young Finns StudySemantic proximity Read ↗

ApoE epsilon3-haplotype modulates Alzheimer beta-amyloid deposition in the brain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.