Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease.

doi:10.7326/0003-4819-141-2-200407200-00013

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Article

Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease.

Annals of internal medicine - 20 Jul 2004

Song Yiqing, Stampfer Meir J, Liu Simin

Abstract excerpt

BACKGROUND: Apolipoprotein E (apoE) genotypes play critical roles in lipid metabolism and are believed to influence risk for coronary heart disease (CHD). Despite many population studies, however, the impact of apoE polymorphism on risk for CHD remains uncertain. PURPOSE: To qualitatively and quantitatively assess the evidence regarding the relation of apoE polymorphism to CHD risk. DATA SOURCES: All relevant...

Topics

Apolipoproteins E
Bayes Theorem
Coronary Disease
Genetic Heterogeneity
Genotype
Humans
Lipid Metabolism
Risk Factors
Sensitivity and Specificity

Source

Open in PubMed

Identifiers

PMID: 15262670
DOI: 10.7326/0003-4819-141-2-200407200-00013

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