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Article

Serum cholesterol, apolipoprotein E genotype and depressive symptoms in elderly European men: the FINE study.

Journal of affective disorders - 1 Jun 2009

Giltay Erik J, van Reedt Dortland Arianne K B, Nissinen Aulikki, Giampaoli Simona, van Veen Tineke, Zitman Frans G, Bots Sinikka, Kromhout Daan

Abstract excerpt

BACKGROUND: Cohort and case-control studies found that lower serum total cholesterol is associated with depression. It is, however, unclear whether low cholesterol or its lipoprotein fractions are causally related to depression. Using a Mendelian randomization design, the potential association between apolipoprotein E (APOE) genotype (affecting lifetime cholesterol levels) and depressive symptoms was studied....

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Source

Identifiers

PMID: 18990452
DOI: 10.1016/j.jad.2008.10.004

Genes

APOE
SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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