Article
Population stratification in a case-control study of brain arteriovenous malformation in Latinos.
Neuroepidemiology - 1 Jan 2008
Kim Helen, Hysi Pirro G, Pawlikowska Ludmila, Choudhry Shweta, González Burchard Esteban, Kwok Pui-Yan, Sidney Stephen, McCulloch Charles E, Young William L
Abstract excerpt
BACKGROUND: Genetic association studies conducted in admixed populations may be confounded by population stratification resulting in spurious associations. The purpose of this pilot study was to determine the presence and effect of population stratification in a case-control study of brain arteriovenous malformation (BAVM). METHODS: We tested 83 ancestry informative markers in BAVM cases and healthy controls of...
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