Article
Brain arteriovenous malformations are associated with interleukin-1 cluster gene polymorphisms.
Neurosurgery - 1 Jan 2012
Fontanella Marco, Rubino Elisa, Crobeddu Emanuela, Gallone Salvatore, Gentile Salvatore, Garbossa Diego, Ducati Alessandro, Pinessi Lorenzo, Rainero Innocenzo
Abstract excerpt
BACKGROUND: Brain arteriovenous malformations (BAVMs) are a rare but important cause of hemorrhagic stroke in young adults. Functional polymorphisms in proinflammatory cytokines have been associated with various cerebrovascular phenotypes, including ischemic stroke, aneurysmal subarachnoid hemorrhage, and BAVM. OBJECTIVE: To investigate whether functional polymorphisms in the IL-1α, IL-1β, and IL-1RN genes are...
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