Article
Comparison of three methods to estimate genetic ancestry and control for stratification in genetic association studies among admixed populations.
Human genetics - 1 Dec 2005
Tsai Hui-Ju, Choudhry Shweta, Naqvi Mariam, Rodriguez-Cintron William, Burchard Esteban González, Ziv Elad
Abstract excerpt
Population stratification may confound the results of genetic association studies among unrelated individuals from admixed populations. Several methods have been proposed to estimate the ancestral information in admixed populations and used to adjust the population stratification in genetic association tests. We evaluate the performances of three different methods: maximum likelihood estimation, ADMIXMAP and...
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