Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants of EGFR (142285G>A) and ESR1 (2014G>A) gene polymorphisms and risk of breast cancer.

Molecular and cellular biochemistry - 1 Oct 2012

Sobti Ranbir Chander, Askari Marjan, Nikbakht Mohsen, Singh Neha, Sharma Suresh C, Abitew Abayneh Munshea

Abstract excerpt

Breast cancer is one of the most common cancers in women worldwide. The estrogen receptor alpha (ESR1) and epidermal growth factor receptor (EGFR) have been known to play a vital role in development and progression of breast cancer. The aim of the present study was to determine the relationship, if any, between genetic polymorphism in (ESR1) 2014G>A (T594T) and (EGFR) 142285G>A (R521K) with risk of breast cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to ErbB Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Estrogen Receptor alpha

Share to Genetic Association Studies

Share to Polymorphism, Genetic

Share to Prognosis

Share to Risk Factors

Source

Identifiers

PMID: 22810499
DOI: 10.1007/s11010-012-1384-x

Genes

EGFR
ESR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants of EGFR (142285G>A) and ESR1 (2014G>A) gene polymorphisms and risk of breast cancer.PMID 22810499Read ↗

Genetic polymorphisms in the EGFR (R521K) and estrogen receptor (T594T) genes, EGFR and ErbB-2 protein expression, and breast cancer risk in Tunisia.Semantic proximity Read ↗

Genetic polymorphisms of ESR1, ESR2, CYP17A1, and CYP19A1 and the risk of breast cancer: a case control study from North India.Semantic proximity Read ↗

Impact of ESR1 Polymorphisms on Risk of Breast Cancer in the Chinese Han PopulationSemantic proximity Read ↗

Estrogen Receptor 1 Gene (ESR1) rs2234693 Polymorphism and Breast Cancer Risk in Saudi Women.Semantic proximity Read ↗

Impact of ESR1 Polymorphisms on Risk of Breast Cancer in the Chinese Han Population.Semantic proximity Read ↗

Estrogen receptor 1 (ESR1) genetic variations in cancer risk: a systematic review and meta-analysis.Semantic proximity Read ↗

Estrogen receptor alpha gene polymorphism and breast cancer.Semantic proximity Read ↗

Association of estrogen receptor-beta (ESR2) polymorphism and cancer risk: a meta-analysis.Semantic proximity Read ↗

Association of ESR1, HER1, and HER2 Polymorphisms with Breast Cancer Risk in the KP Population, A Case-Control Study.Semantic proximity Read ↗

Genetic polymorphism of ESR1 rs2881766 increases breast cancer risk in Korean women.Semantic proximity Read ↗

Estrogen Receptor Alpha (ESR1) gene polymorphism (rs2234693 and rs2046210) with breast cancer risk in Pashtun population of Khyber PakhtunkhwaSemantic proximity Read ↗

A common polymorphism near the ESR1 gene is associated with risk of breast cancer: evidence from a case-control study and a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.