Article

Epidermal Growth Factor Receptor Regulates Beclin-1 in Hyperoxic Acute Lung Injury

2024-05-27

Abstract excerpt

<h4>ABSTRACT</h4> While delivery of supplemental oxygen is a life-saving therapy, exposure to high levels of oxygen, called hyperoxia, is associated with increased mortality in the intensive care unit (ICU). Hyperoxia leads to oxidant-mediated acute lung injury (ALI) and pulmonary cell death, called hyperoxic acute lung injury (HALI). Elucidation of molecular mechanisms in HALI could identify therapeutic targets...

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Literature Corpus work: 8938b77f-5833-5dac-98f7-adc9f2f5e1c9
DOI: 10.1101/2024.05.24.595621

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