Article
Capturing protein tails by CAP-Gly domains.
Trends in biochemical sciences - 1 Nov 2008
Steinmetz Michel O, Akhmanova Anna
Abstract excerpt
Cytoskeleton-associated protein-glycine-rich (CAP-Gly) domains are protein-interaction modules implicated in important cellular processes and in hereditary human diseases. A prominent function of CAP-Gly domains is to bind to C-terminal EEY/F-COO(-) sequence motifs present in alpha-tubulin and in some microtubule-associated protein tails; however, CAP-Gly domains also interact with other structural elements...
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