Article
Mutation screening of the BRCA1 gene in sporadic breast cancer in southern Chinese populations.
Breast (Edinburgh, Scotland) - 1 Dec 2008
Haitian Zhang, Yunfei Lu, Jian Zeng, Jian Lin, Qinghua Liao, Fuqiang Wan
Abstract excerpt
The comparison of freshly collected breast cancer tissue DNA with that of the matched blood specimens of 144 patients was studied, and breast tissue from 30 unrelated normal women without cancer was selected as controls. The entire BRCA1 coding sequence was amplified by PCR with primers especially designed for comprehensive mutation screening by single-strand conformation polymorphism (SSCP) analysis....
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