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Analysis of BRCA1 and BRCA2 mutations in southern Iranian Breast cancer patients.

Archives of Iranian medicine - 1 Nov 2009

Fattahi Mohammad Javad, Mojtahedi Zahra, Karimaghaee Nazanin, Talei Abdul-Rasoul, Banani Seeyed Javad, Ghaderi Abbas

Abstract excerpt

The germline mutations of breast cancer susceptibility genes 1 (BRCA1) and breast cancer susceptibility genes 1 (BRCA2) have been associated with a significant increase in breast cancer risk and certain other cancers. Among the most known mutations in these tumor suppressor genes are 5382insC and 185delAG in BRCA1 and 6174delT in BRCA2. The aim of the current study was to investigate the frequency of these BRCA1...

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Base Sequence
Breast Neoplasms
BRCA2 gene
Genes, BRCA1
Genes, BRCA2

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Molecular Sequence Data

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PMID: 19877752

Genes

BRCA1
BRCA2

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