Article
Missense alterations of BRCA1 gene detected in diverse cancer patients.
Anticancer research - 1 Jan 2000
Shen D, Wu Y, Chillar R, Vadgama J V
Abstract excerpt
The mutations in the breast cancer susceptible gene BRCA1 are responsible for about 50% of inherited breast cancers and confer increased risk of breast and ovarian cancer to its carriers. BRCA1 gene mutations may also be related with other types of cancers such as prostate cancer and colorectal cancer. The goal of this study was to investigate if BRCA1 mutation could be detected in diverse types of cancers. We...
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