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Article

Somatic mutations in the BRCA1 gene in Chinese sporadic breast and ovarian cancer.

Oncogene - 12 Aug 1999

Khoo U S, Ozcelik H, Cheung A N, Chow L W, Ngan H Y, Done S J, Liang A C, Chan V W, Au G K, Ng W F, Poon C S, Leung Y F, Loong F, Ip P, Chan G S, Andrulis I L, Lu J, Ho F C

Abstract excerpt

Inherited mutations in the BRCA1 gene confer increased susceptibility to breast and ovarian cancer. Its role in sporadic carcinogenesis is not well defined. Somatic mutations in breast cancers have not been reported and to date there are only three reports of somatic mutations in sporadic ovarian...

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Source

Identifiers

PMID: 10467410
DOI: 10.1038/sj.onc.1202847

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10467410-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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