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Article

Identification of TmcN as a pathway-specific positive regulator of tautomycetin biosynthesis in Streptomyces sp. CK4412.

Microbiology (Reading, England) - 1 Oct 2008

Hur Yoon-Ah, Choi Si-Sun, Sherman David H, Kim Eung-Soo

Abstract excerpt

Tautomycetin (TMC) is a novel activated T-cell-specific immunosuppressive compound with a unique structure, containing an ester bond linkage between a terminal cyclic anhydride moiety and a linear polyketide chain bearing an unusual terminal alkene. A 3 kb gene, tmcN, with a deduced product of 10...

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Identifiers

PMID: 18832298
DOI: 10.1099/mic.0.2008/018903-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18832298-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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