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Article

Mining of a streptothricin gene cluster from Streptomyces sp. TP-A0356 genome via heterologous expression.

Science China. Life sciences - 1 Jul 2013

Li Jine, Guo Zhengyan, Huang Wei, Meng Xiangxi, Ai Guomin, Tang Gongli, Chen Yihua

Abstract excerpt

Streptothricins (STs) are used commercially to treat bacterial and fungal diseases in agriculture. Mining of the sequenced microbial genomes uncovered two cryptic ST clusters from Streptomyces sp. C and Streptomyces sp. TP-A0356. The ST cluster from S. sp. TP-A0356 was verified by successful heterologous expression in Streptomyces coelicolor M145. Two new ST analogs were produced together with streptothricin F...

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PMID: 23832251
DOI: 10.1007/s11427-013-4504-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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