Article
A MarR-family transcriptional factor MapR positively regulates actinorhodin production in Streptomyces coelicolor.
FEMS microbiology letters - 25 Sept 2020
Xu Zhong, Li Yuanyuan
Abstract excerpt
Production of secondary metabolites is tightly regulated by transcriptional regulators in Streptomyces. Many regulators have been identified by gene disruption in Streptomyces; however, there are still unknown regulatory genes yet to be revealed due to gene silence under laboratory culture conditions. In present study, a T7 expression system was used to identify novel regulators by gene deletion and...
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