Article
TGF-beta1 genotype and phenotype in breast cancer and their associations with IGFs and patient survival.
British journal of cancer - 21 Oct 2008
Mu L, Katsaros D, Lu L, Preti M, Durando A, Arisio R, Yu H
Abstract excerpt
Transforming growth factor-beta (TGF-beta)-mediated signals play complicated roles in the development and progression of breast tumour. The purposes of this study were to analyse the genotype of TGF-beta1 at T29C and TGF-beta1 phenotype in breast tumours, and to evaluate their associations with IGFs and clinical characteristics of breast cancer. Fresh tumour samples were collected from 348 breast cancer patients....
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